I see the pre-film ads and trivia slides so many times that I can usually tune them out, but I saw one before 2 DAYS IN PARIS that looked like a joke ripped from an infographic in The Onion. The bon mot used for movie quotation guessing was, "Men."
Now I'm not the best when it comes to remembering lines from movies, but off the top of my head, I can't think of any single word quotes that have caught the public's imagination, let alone one comprised of an unremarkable word. Yes, I know that many of these movie trivia questions are often thinly veiled attempts to promote current releases, but this has to set a baseline for Worst Quotation Ever.
Have you figured it out? This witticism was uttered by Abigail Breslin in NO RESERVATIONS. Remember it well. It's destined to be one of the great lines in cinema's history.